Subcorneal Pustular Dermatosis Exhibiting a High Serum TARC/CCL17 Level

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Subcorneal Pustular Dermatosis Exhibiting a High Serum TARC/CCL17 Level

Subcorneal pustular dermatosis (SPD) is a rare, relapsing, symmetric sterile pustular eruption that dominantly involves flexural areas. It is considered one form of neutrophilic dermatoses, which are associated with interleukin (IL)-17-producing T helper (Th) 17 cells that induce IL-8 production. We have previously reported that Th17 might be involved in the pathomechanism of Th2-dominant atopi...

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Subcorneal pustular dermatosis.

Subcorneal dermatosis is a chronic relapsing pustular eruption which has been recognised for 20 years. The diagnosis can be made only by combining the clinical features of a recurrent eruption mainly on the trunk which spares the mucosae and has the histological appearance of a subcorneal bullae filled with polymorphonuclear leucocytes situated on the surface of normal epidermis. No immunofluor...

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Subcorneal pustular dermatosis in the pediatric age*

Subcorneal pustular dermatosis is a rare pustular eruption which occurs mainly in middle-aged women and rarely during childhood. We report a case of a 15-year-old female with a 4-year history of pustular lesions on the proximal region of the upper limbs with subsequent impairment of the trunk. Physical examination revealed small pustules distributed on the trunk and proximal region of the limbs...

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Subcorneal pustular dermatosis an immnohisto-pathological perspective.

UNLABELLED Subcorneal pustular dermatosis (SPD) represents a chronic, relapsing sterile pustular eruption, involving the trunk and flexoral proximal extremities. A 54-year-old female presented with recurrent, flaccid pustules measuring several millimeters in diameter, on normal and mildly erythematous skin of the groin and submammary areas. Biopsies for hematoxylin and eosin (H&E) examination, ...

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[subcorneal Pustular Dermatosis. (sneddon-wilkinson Disease)].

Subcorneal pustular dermatosis is a disease that has coalescent, flaccid, recurrent pustules. We do not know everything about its etiology or pathogenesis; however, its autoimmune mechanism links it with neoplastic or immunologic diseases. First line treatment is dapsone. We describe the case of a classic subcorneal pustular dermatosis in a patient in who we could not use dapsone (sulpha drugs ...

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ژورنال

عنوان ژورنال: Case Reports in Dermatology

سال: 2013

ISSN: 1662-6567

DOI: 10.1159/000348241